We antagonize them because we are so much better than them. NATO isn't what threatens Putin's regime of cronyism. The fact our western liberal societies are so much better than Putin dominated societies are what threaten and antagonizes the regime.
Israel antagonizes the Arab world because it is a daily reminder how pathetic their societies are in comparison.
The "multipolar world" is mostly envious losers who are threatened by our clear superiority. And because they suck so much, our leaving isn't going to make anything better. Afghanistan isn't better for our leaving. It sucks. Giving Putin to Ukraine isn't going to make Ukraine better. It is going to make is suckier. Which is why the Ukrainian people are fighting so hard to make it not happen.